FPIES Diagnosis Process

Food protein-induced enterocolitis syndrome (FPIES) is not an easy condition to diagnose. Blood allergy tests are not reliable as they only look for IgE-mediated food allergies, which FPIES is not. There is no actual laboratory test available for diagnosing FPIES.

If FPIES is suspected, based on symptoms alone, the only way to get an accurate diagnosis is through an oral food challenge. A small amount of the food allergen is fed to the patient under medical supervision to observe the symptoms. If a reaction occurs, a positive FPIES diagnosis is made. A diagnosis may take several weeks, because the food allergens need to be introduced to the child’s diet one at a time to identify which ones trigger the reaction.

There is no current laboratory test for FPIES as it is a condition caused by a non-IgE-mediated food allergy. Oftentimes, it can take time to get a diagnosis as the symptoms resemble those of a severe stomach flu.

Our Products for FPIES

Neocate® is a family of hypoallergenic, amino acid-based specialized formulas for use under medical supervision and is indicated for cow milk allergy, multiple food allergies and related GI and allergic conditions. Talk to your healthcare provider about product recommendations.
Neocate Nutra is suitable for use in children and infants older than 6 months of age (not suitable as sole source of nutrition). Neocate Nutra is not intended for bottle or tube feeding.


Within days of his birth, Roland showed signs of dairy protein intolerance. He wasn’t able to nurse and was tube-fed his mom’s pumped breast milk. His mom eliminated dairy, then soy, and eventually all allergens from her diet, but his condition worsened over time. He was eventually diagnosed with FPIES. Neocate, an amino acid-based formula, recommended by his HCP helped to manage his FPIES symptoms, and Roland became a smiling, easy to care for baby.*

Roland’s** Story

*Individual results may vary.
**A patient’s story from the US

Born completely healthy, Kennedy started having blood in her stool at around 2 weeks. Her condition started improving with Neocate® Infant*. However, at 6 months, almost every solid food caused a vomiting reaction. An allergist formally diagnosed Kennedy with FPIES. Kennedy was 100% tube fed for the following months. Her FPIES RD gave us Neocate Splash after the age of 1. For the 1st time, she drank half of it in one go!**

Kennedy’s*** Story

*Sold in Canada as Neocate® DHA & ARA infant formula
**Individual results may vary.
***A patient’s story from the US

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