What are the causes of Eosinophilic Esophagitis

Like other food allergy and gastrointestinal (GI)-related disorders, healthcare professionals are still searching for an exact cause for Eosinophilic Esophagitis (EoE). They are still unsure of why some people get EoE and others don’t. People with EoE can also have asthma, other food allergies, and/or seasonal allergies.

There are four (4) common risk factors found in EoE:

Sex: The sex of a child can be a risk factor for EoE. Males make up three-quarters of those diagnosed with the condition, but girls can have it too.

Race: Caucasians and South Asians are more likely to have EoE.

Atopy: Atopy is a genetic tendency to develop an allergic disease such as rhinitis, asthma, environmental allergies, and eczema. Two-thirds of those with EoE have some atopy; however, one-third of those with EoE are not atopic.

Family History: If there is a family history, a child is at greater risk.

EoE is commonly triggered by two or more food allergens, the most common being milk protein. Symptoms appear when a large number of eosinophils collect in the esophagus. It is unknown why the allergies cause these white blood cells to move to the esophagus. However, what we do know is that EoE is a chronic condition that usually persists in most individuals. We can only manage and alleviate the symptoms.

EoE is typically a food allergy-related condition that is still under research. The causes are not clear yet.

Our Products for Eosinophilic Esophagitis

Neocate® is a family of hypoallergenic, amino acid-based specialized formulas for use under medical supervision and is indicated for cow milk allergy, multiple food allergies and related GI and allergic conditions. Talk to your healthcare provider about product recommendations.
Neocate Nutra is suitable for use in children and infants older than 6 months of age (not suitable as sole source of nutrition). Neocate Nutra is not intended for bottle or tube feeding.


Remington is a young adult who was diagnosed with Eosinophilic Esophagitis (EoE), at the age of 3, and was removed from all foods at the age of 4. His sole source of nutrition is still Neocate® Splash, as currently he has no safe foods in his diet. Nonetheless, he goes to school, plays baseball, and works out daily to stay in shape.*

Remington**’s story

*Individual results may vary.
**A patient’s story from the US

Karyn was diagnosed with eosinophilic esophagitis (EoE) at 17 months. Shortly after introducing Neocate®, her parents noticed her symptoms improved. Nowadays, Karyn uses Neocate® Junior at home and brings Neocate® Splash to school for her lunch. She likes how it’s so similar to other kids’ drink boxes.*

Karyn’s** Story

*Individual results may vary.
**A patient’s story from the US

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